Weight Loss Maintenance in Adults

A randomised controlled trial of a 12-month multi-component intervention versus a less intensive version on study participants' maintenance of weight loss

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN35774128

Enrollment

950

Registered

2010-01-12

Start date

2010-04-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity/public health/behaviour change Nutritional, Metabolic, Endocrine Obesity

Interventions

1. Intense intervention - six one-to-one motivational interviewing (MI) sessions plus four group sessions and 11 brief MI phone calls 2. Less intense intervention - two one-to-one MI sessions plus fou

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Obese adults aged 18 - 70 years, either sex 2. Current or previous body mass index (BMI) of 30 or above 3. Lost at least 5% body weight (by pharmacological, lifestyle and/or behavioural methods) during the last 12 months 4. Independent verification of weight loss

Exclusion criteria

Exclusion criteria: 1. Unable to comply with study protocol, e.g., due to mental health problems, terminal illness or competence in English 2. Pregnant women

Design outcomes

Primary

Measure	Time frame
BMI at 3 years from randomisation	—

Secondary

Measure	Time frame
1. Waist circumference, measured at baseline, post intervention, 12 months and 24 months after the end of the intervention 2. Waist to hip ratio, measured at baseline, post intervention, 12 months and 24 months after the end of the intervention 3. Body fat distribution, measured at baseline, post intervention, 12 months and 24 months after the end of the intervention 4. Self-report physical activity, collected at baseline, 6 months (during intervention), post-intervention, 12 month follow-up after end of intervention and 24 months after the end of the intervention 5. Proportion maintaining weight loss, measured post-intervention and at 12 and 24 months after intervention 6. Self report dietary intake, collected at baseline, 6 months (during intervention), post-intervention, 12 month follow-up after end of intervention and 24 months after the end of the intervention 7. Health-related quality of life, collected at baseline, 6 months (during intervention), post-intervention, 12 month follow-up after end of intervention and 24 months after the end of the intervention 8. Health resource usage, collected at baseline, 6 months (during intervention), post-intervention, 12 month follow-up after end of intervention and 24 months after the end of the intervention 9. Binge eating, measured post-intervention and at 12 and 24 months after intervention 10. Psychological well being and duration of participation and drop out from intervention, measured post-intervention and at 12 and 24 months after intervention	—

Measure

Time frame

1. Waist circumference, measured at baseline, post intervention, 12 months and 24 months after the end of the intervention 2. Waist to hip ratio, measured at baseline, post intervention, 12 months and 24 months after the end of the intervention 3. Body fat distribution, measured at baseline, post intervention, 12 months and 24 months after the end of the intervention 4. Self-report physical activity, collected at baseline, 6 months (during intervention), post-intervention, 12 month follow-up after end of intervention and 24 months after the end of the intervention 5. Proportion maintaining weight loss, measured post-intervention and at 12 and 24 months after intervention 6. Self report dietary intake, collected at baseline, 6 months (during intervention), post-intervention, 12 month follow-up after end of intervention and 24 months after the end of the intervention 7. Health-related quality of life, collected at baseline, 6 months (during intervention), post-intervention, 12 month follow-up after end of intervention and 24 months after the end of the intervention 8. Health resource usage, collected at baseline, 6 months (during intervention), post-intervention, 12 month follow-up after end of intervention and 24 months after the end of the intervention 9. Binge eating, measured post-intervention and at 12 and 24 months after intervention 10. Psychological well being and duration of participation and drop out from intervention, measured post-intervention and at 12 and 24 months after intervention

—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 17, 2026