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Secondary prevention after first stroke

Cluster randomised trial in a Primary Care database: utilising electronic patient records for intervention research into secondary prevention after first stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN35701810
Enrollment
100
Registered
2010-03-17
Start date
2010-04-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke Circulatory System Stroke, not specified as haemorrhage or infarction

Interventions

A series of electronic prompts will be activated at each consultation by patients with previous stroke, to promote adherence with evidence-based recommendations for secondary prevention of stroke and

Sponsors

The Wellcome Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All stroke patients (no age limit, either sex) 2. Registered at the practice for at least three years at the trial start date 3. First diagnosis of stroke recorded in the 24 month period before the trial start date 4. Medical code for stroke is entered during the consultation 5. Patient's electronic medical record includes previous stroke medical codes

Exclusion criteria

Exclusion criteria: No eligible patients will be excluded from the analysis, to avoid bias.

Design outcomes

Primary

MeasureTime frame
Difference in mean systolic blood pressure (BP) between intervention and control groups at 12 months adjusted for pre-intervention mean systolic BP

Secondary

MeasureTime frame
Measured at 12 months follow-up: 1. Mean diastolic blood pressure 2. Mean cholesterol concentration 3. Proportion of patients whose eligibility for anticoagulants/antiplatelet drugs is defined 4. Proportion of eligible patients that receive anticoagulant/antiplatelet drugs 5. Prescription adherence with prescribed medicines 6. Occurrence and hospitalisation with vascular events including transient ischaemic attack (TIA)/stroke, myocardial infarction, new-onset angina and mortality

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 25, 2026