The impact of a hematocrit of 20% during normothermic cardiopulmonary bypass for elective coronary artery bypass graft surgery on oxygen delivery and clinical outcome: a randomised controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN35655335

Enrollment

Registered

2006-01-19

Start date

2004-02-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease requiring surgical revascularisation Circulatory System Coronary artery disease

Interventions

Hemodilution during cardiopulmonary bypass achieving a hematocrit of 20% versus 25%.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Coronary artery disease patients to about to undergo coronary artery bypass graft surgery.

Exclusion criteria

Exclusion criteria: 1. Ejection fraction less than 40% 2. Chronic Obstructive Pulmonary Disease (COPD) 3. Renal insufficiency 4. Peripheral artery disease 5. Hepatic dysfunction

Design outcomes

Primary

Measure	Time frame
Oxygen delivery and oxygen consumption.	—

Secondary

Measure	Time frame
1. Myocardial infarction 2. Renal insufficiency measured as creatinine and urine volume 3. Neurological deficits displayed as agitated arousal reactions and stroke	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 2, 2026