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Ultrasound guided continous serratus anterior plane block: dexmedetomidine as an adjunctive analgesic with levobupivacine for post thoracotomy pain

Ultrasound guided continous serratus anterior plane block :dexmedetomidine as an adjunctive analgesic with levobupivacine for post thoracotomy pain: a prospective randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN35517318
Enrollment
50
Registered
2017-04-19
Start date
2017-04-10
Completion date
Unknown
Last updated
2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-thoracotomy pain Surgery

Interventions

Patients will be randomized by double-blind simple randomization to two groups. 1. 25 patients will receive a bolus of 30 ml of 0.25% levobupivacaine followed by an infusion of 5 ml/ho
subsequently every half an hour for the next 2 hours and then 2 hourly for the next 12 hours. As soon as the patient is alert enough VAS pain score will be recorded every 2 hours 2. To

Sponsors

National Cancer Institute, Cairo University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age from 20-60 2. ASA 2 or 3 3. Undergoing elective thoracic surgery

Exclusion criteria

Exclusion criteria: 1. Refusal of the patient 2. Coagulopathy 3. Severe cardiac or renal impairment or hepatic disease 4. Known allergy to the study drugs

Design outcomes

Primary

MeasureTime frame
Postoperative pain at rest and coughing, measured by VAS pain score (10 mm vertical scale from 0-10 where zero means no pain and 10 is the worst pain) every 2h in the first 24h postoperative

Secondary

MeasureTime frame
1. Postoperative opioid consumption, recorded by staff during first 24 hours postoperative 2. Adverse effects including nausea, vomiting, hypotension and cardiac arrhythmias, recorded by staff in the first 24h postoperative

Countries

Egypt

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 21, 2026