Enhancing vision performance and comfort Eye Diseases Vision performance
Conditions
Interventions
This double blind placebo controlled study has two study arms:
1. The placebo formulation contains: lactose, cellulose, microcrystalline, magnesium stearate (core) and filmbuilding mat
vision questionnaire
macular pigment measurement
variety of vision performance tests (e.g. contrast sensitivity and glare recovery).
Contact for public queries:
Ms Eithne Connolly
MPRG project manager
Sponsors
Enterprise Ireland (Ireland)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Any race 2. Male or female 3. Aged 18 to 40 years 4. No presence of ocular pathology 5. Visual acuity of at least 6/18 in the study eye
Exclusion criteria
Exclusion criteria: 1. Outside age range 18 to 40 2. Pregnancy 3. Presence of ocular pathology 4. Cataract
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To determine whether a person's macular pigment optical density relates to visual performance and/or ocular comfort, measured using heterochromatic flicker photometry 2. To determine whether augmentation (through supplementation) of a person's macular pigment optical density results in enhanced visual performance and/or improved ocular comfort, measured via questionnaire and by a variety of objective vision assessment techniques The primary and secondary outcome measures will be assessed at each study visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To determine whether changes in serum concentrations of lutein and zeaxanthin are associated with changes in macular pigment levels in normal subjects 2. To determine whether objective assessments of visual performance are associated with subjective, questionnaire based, assessments of visual performance The primary and secondary outcome measures will be assessed at each study visit. | — |
Countries
Ireland
Outcome results
None listed