Skip to content

The effect of 'goal directed' fluid management during gynaecological oncology surgery using the oesophageal Doppler probe

The effect of intra-operative fluid optimisation using the oesophageal Doppler monitor in gynaecological oncology surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN35322992
Enrollment
140
Registered
2010-08-04
Start date
2010-11-01
Completion date
Unknown
Last updated
2017-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynaecological oncology surgery Surgery Surgical recovery

Interventions

Two groups: control and protocol group. Both groups will have DP6 Doppler probe (product code 9070-7001) inserted at the time of intubation. All patients will have standard pre-operative, intra-oper

Sponsors

Gateshead Health NHS Foundation Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Patients aged 20 - 85 years, female 2. Recruited from the Queen Elizabeth Hospital, Gateshead 3. Written informed consent 4. Undergoing elective major gynaecological oncology surgery for ovarian, endometrial and cervical carcinoma

Exclusion criteria

Exclusion criteria: Contraindication to oesophageal Doppler use: 1. Oesophageal surgery or stent 2. Oesophageal stricture 3. Oesophageal varices 4. Pharyngeal pouch 5. Moderate/severe aortic valve disease 6. Patient refusal

Design outcomes

Primary

MeasureTime frame
The aim of this study is to compare the effect of a target driven intra-operative intravenous fluid management using oesophageal Doppler to a standard fluid regimen on complication rate after surgery for corpus uteri, ovarian and cervical cancer. Measured until 5th post-operative day.

Secondary

MeasureTime frame
To evaluate the effect of target driven intra-operative fluid management using oesophageal Doppler on hospital stay, measured on day of discharge.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026