Fermentation and cardiovascular risk factors

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN35312139

Enrollment

Registered

2007-08-02

Start date

2006-11-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes/ obesity Nutritional, Metabolic, Endocrine type 2 diabetes/ obesity

Interventions

Dietary supplementation with either 0 g, 20 g or 40 g resistant starch per day for 12 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy 2. Fasting insulin >60 pmol/l 2. Male and female 18-60 years

Exclusion criteria

Exclusion criteria: 1. Cardiovascular or endocrine diseases 2. Medication likely to affects either lipid or glucose metabolism

Design outcomes

Primary

Measure	Time frame
Insulin sensitivity will be assessed before and after the 12-week intervention by the following: 1. Euglycaemic-hyperinsulinaemic clamp 2. Liver fat content measured by Magnetic Resonance Imaging [MRI]	—

Secondary

Measure	Time frame
The following outcomes are being measured before and after the 12-week intervention: 1. Endothelial function, assessed by Pulse Wave Velocity (PWV) and 24-hour blood pressure recordings 2. Blood inflammatory markers	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026