Topical zinc oxide for open pilonidal sinus wounds: a randomised, double-blind, placebo-controlled multicentre trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN35311675

Enrollment

Registered

2004-09-29

Start date

2002-02-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pilonidal excisional wound Surgery Excision

Interventions

Zinc oxide and polyvinylpyrrolidone versus polyvinylpyrrolidone alone

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients, 18 years or older, with a first-episode of pilonidal abscess requiring surgery are included after giving their written informed consent.

Exclusion criteria

Exclusion criteria: Previous pilonidal surgery, hypersensitivity to zinc, dementia, insufficiency in Danish, pregnancy or lactation.

Design outcomes

Primary

Measure	Time frame
Time to wound closure in days, defined by complete coverage of the wound with visible epithelium.	—

Secondary

Measure	Time frame
Secondary outcomes were: 1. Postoperative antibiotic treatment 2. Re-operations 3. Pain intensity 4. Adverse events Tertiary outcomes were: 1. Serum-zinc levels 2. Sick leave	—

Countries

Denmark

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026