A randomised placebo controlled double blind clinical trial of vitamin D in the treatment of tuberculosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN35212132

Enrollment

500

Registered

2004-05-21

Start date

2003-11-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tuberculosis Infections and Infestations Tuberculosis

Interventions

100,000 IU cholecalciferol or placebo in drinkable ampoule at diagnosis, 5 months and 8 months clinical follow up (i.e. total 300,000 IU).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients diagnosed with tuberculosis (smear positive and smear negative) living in the field site study area

Exclusion criteria

Exclusion criteria: None. Withdrawal if signs of hypercalcaemia or allergy to vitamin D.

Design outcomes

Primary

Measure	Time frame
Clinical status (time to cure by sputum clearance, weight gain, clinical score) after treatment	—

Secondary

Measure	Time frame
Mortality	—

Countries

Guinea-Bissau

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 3, 2026