Periodontitis Oral Health Periodontitis
Conditions
Interventions
Full mouth scaling and root planing, application of a novel hydrophobic gingiva-adhering chlorhexidine-based gel with complex composition vs a standard commercially available 1% chlorhexidine diglucon
Sponsors
lege artis Pharma GmbH + Co. KG (Germany)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age between 40 ? 65 years old, 2. Moderate chronic periodontitis (two or more interproximal sites with = 4 mm clinical CAL [not on the same tooth] or two or more interproximal sites with = 5 mm PD, also not on the same tooth [according to the CDC-AAP definition]) 3. At least 20 teeth present in the mouth 4. No periodontal therapy during the last 2 years 5. No antibiotic or anti-inflammatory drugs intake during the last 6 months before baseline examination 6. Absence of fixed or removable prosthesis 7. Good general health
Exclusion criteria
Exclusion criteria: 1. Either pregnant or nursing 2. Any diseases with influence on the periodontal diseases 3. Allergies to the components of the products used in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical measurements and photographs were taken at baseline and at follow-up post-operatory 3 and 6 months for both primary and secondary outcome measures. 1. Clinical attachment level 2. Frequency of detection of periodontopathogenic bacteria 3. Enzymatic activity of neutrophil elastase and myeloperoxidase | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Pocket depth 2. Gingival recession 3. Plaque indices | — |
Countries
Romania
Outcome results
None listed