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How different types of strength training affect ankle muscles and tendons

Effects of eccentric quasi-isometric and eccentric training on mechanical and architectural properties of the ankle plantar flexors: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN35199955
Enrollment
45
Registered
2025-11-13
Start date
2025-11-06
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

This study focuses on muscle–tendon adaptation and function in healthy adults. It does not involve patients with pathological conditions. The research investigates how different eccentric loading strategies affect the mechanical and architectural properties of the ankle plantar flexor muscles and Achilles tendon. Other

Interventions

Participants will be randomly assigned to one of three groups: Eccentric quasi-isometric (EQI) training: Participants will complete a 6-week EQI training program targeting the right ankle plantar fle

Sponsors

University of Primorska, Faculty of Health Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Healthy adults (male and female) aged 18–30 years. 2. No musculoskeletal injuries in the past 3 months. 3. No ankle injuries in the past 12 months. 4. Regular participation in resistance training (=2–3 sessions per week during the past 6 months). 5. Ability and willingness to participate in all testing and training sessions. 6. Agreement to maintain usual daily physical activity and to refrain from any additional resistance or proprioceptive training targeting the ankle plantar flexors during the study period.

Exclusion criteria

Exclusion criteria: 1. Presence of chronic infectious or metabolic disease. 2. Cardiovascular or respiratory disorder that limits physical activity. 3. Diagnosed neurological condition (e.g., multiple sclerosis, Parkinson’s disease). 4. Current or recent musculoskeletal injury not meeting inclusion criteria. 5. Use of medications that may influence physical performance or neuromuscular function. 6. Pregnancy.

Design outcomes

Primary

MeasureTime frame
1. Muscle fascicle length is measured using panoramic B-mode ultrasound imaging of the medial and lateral gastrocnemius at baseline and 1 week after completion of the 6-week intervention 2. Muscle pennation angle is measured using panoramic B-mode ultrasound imaging of the medial and lateral gastrocnemius at baseline and 1 week after completion of the 6-week intervention 3. Muscle thickness is measured using panoramic B-mode ultrasound imaging of the medial and lateral gastrocnemius at baseline and 1 week after completion of the 6-week intervention

Secondary

MeasureTime frame
1. Isometric peak torque of the ankle plantar flexors is measured using an isokinetic dynamometer (HumacNorm, USA) under isometric conditions at baseline and 1 week after completion of the 6-week intervention 2. Concentric peak torque of the ankle plantar flexors is measured using an isokinetic dynamometer (HumacNorm, USA) at 60°/s at baseline and 1 week after completion of the 6-week intervention 3. Eccentric peak torque of the ankle plantar flexors is measured using an isokinetic dynamometer (HumacNorm, USA) at 60°/s at baseline and 1 week after completion of the 6-week intervention 4. Ankle dorsiflexion range of motion is measured using a goniometer in open- and closed-kinetic-chain positions at baseline and 1 week after completion of the 6-week intervention 5. Perceived muscle soreness is measured using a 10-point numerical rating scale before and after each training session during the 6-week intervention 6. Perceived session difficulty is measured using a 10-point numerical rating scale before and after each training session during the 6-week intervention

Countries

Slovenia

Contacts

Public ContactŽiga Kozinc
ziga.kozinc@fvz.upr.si+38640161503

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 15, 2026