MRSA infection Infections and Infestations
Conditions
Interventions
Control group: When each patient is admitted to and discharged from the ward, nursing staff will take a set of MRSA screening swabs. MRSA screening on admission is already in practice at King's Colleg
Sponsors
Guy's & St Thomas' NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All adult admissions to study wards who are screened within 48 hours of admission to and discharge from the study wards are eligible for inclusion.
Exclusion criteria
Exclusion criteria: Patients who are: 1. MRSA positive on any specimens taken up to 5 days before the current admission 2. MRSA culture positive on study ward MRSA admission screen 3. Are not swabbed for MRSA on admission 4. Have MRSA admission screening swabs taken >48 hours after study ward admission 5. MRSA discharge screens which do not contain nose, throat and groin or perineum swabs 6. Are not swabbed for MRSA on discharge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRSA transmission rates = the ratio of patients who are positive for MRSA by conventional microbiological method at the time of admission to the number of patients who are negative for MRSA on admission screens by conventional microbiological method and subsequently become positive by discharge on any specimen taken >48 hours after admission. The primary outcome will be analysed using generalised estimating equations with Poisson family, log link and robust standard errors will be used to fully account for correlations of observations made within wards, periods and ward periods. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Appropriate and inappropriate isolation days 2. MRSA carriage rate and acquisition rate Secondary outcomes will be measured after one month. | — |
Countries
United Kingdom
Outcome results
None listed