Proctocolectomy and ileal pouch anal anastomosis: total mesorectal excision versus Close Rectal excision

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN35140084

Enrollment

Registered

2007-08-23

Start date

2006-06-23

Completion date

Unknown

Last updated

2021-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ileal pouch anal anastomosis Surgery Surgical techniques

Interventions

Close rectal dissection of the rectum.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Indication for proctocolectomy with construction of ileoanal pouch 2. Ulcerative Colitis or Familial Adenomatous Polyposis 3. Informed consent

Exclusion criteria

Exclusion criteria: 1. Aged less than 18 years 2. American Society of Anaesthesiologists (ASA) III/IV 3. (Severe) postoperative complication 4. Emergency procedure

Design outcomes

Primary

Measure	Time frame
1. Baseline volume and distensibility of the pouch, measured at least one year after surgery 2. Continence, measured through questionnaires at 1, 3, 6 and 12 months following surgery 3. Quality of life, measured through questionnaires at 1, 3, 6 and 12 months following surgery	—

Secondary

Measure	Time frame
1. Morbidity 2. Blood loss	—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026