Pre-transplant machine perfusion of heart-beating donor kidneys prior to renal transplantation

A multi-centre, randomised, controlled study of pre-transplant machine perfusion of heart-beating donor kidneys prior to renal transplantation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN35082773

Enrollment

200

Registered

2005-05-10

Start date

2006-06-28

Completion date

Unknown

Last updated

2017-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney preservation prior to transplantation Surgery Kidney transplant

Interventions

Machine perfusion of the kidney before transplantation versus simple cold storage

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients (aged 18 years and over, either gender) undergoing transplantation of a kidney from a heart-beating cadaver donor.

Exclusion criteria

Exclusion criteria: Added 24/02/2009: Multi-organ recipient

Design outcomes

Primary

Measure	Time frame
Incidence of delayed graft function at 7 days	—

Secondary

Measure	Time frame
1. Patient survival 2. Graft survival 3. Graft function - estimated glomerular filtration rate (GFR) 4. Acute rejection incidence 5. Acute rejection severity 6. Incidence of steroid resistant rejection, defined as the need for ATG therapy	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026