Total knee arthroplasty versus patellofemoral arthroplasty in patients with severe arthritis of the patellofemoral joint

The Warwick patellofemoral arthroplasty trial: a randomised clinical trial of total knee arthroplasty versus patellofemoral arthroplasty in patients with severe arthritis of the patellofemoral joint

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN34863373

Enrollment

Registered

2009-09-02

Start date

2009-03-01

Completion date

Unknown

Last updated

2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellofemoral osteoarthritis Musculoskeletal Diseases Polyarthrosis

Interventions

All potential participants for this study will be identified by Orthopaedic Consultants in the arthroplasty clinics. Eligible patients will be randomised in a 1:1 allocation to a TKA or PFA. The patie

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Medically fit for an operation 2. Severe isolated patellofemoral osteoarthritis of the knee 3. Deemed suitable for a PFA by the consultant surgeon 4. Both male and female patients, aged 18 years and older

Exclusion criteria

Exclusion criteria: 1. Unfit for an operation 2. Tibiofemoral arthritis of the knee

Design outcomes

Primary

Measure	Time frame
Western Ontario and McMaster Osteoarthritis Index (WOMAC), used to determine knee function at 6 weeks, 3 months, 6 months and 12 months	—

Secondary

Measure	Time frame
Measured pre-operatively, 3, 6 and 12 months post-operatively: 1. UCLA Knee Rating Score 2. Oxford Knee Score 3. EuroQOl 4. Knee Society Score	—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 27, 2026