A prospective randomised controlled trial of open access endoscopy and near patient testing for Helicobacter pylori antibodies in primary care

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN34856269

Enrollment

430

Registered

2004-01-23

Start date

1995-03-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peptic ulcer disease Digestive System Gastro-oesophageal reflux disease

Interventions

Under 50 years: Near patient testing for H. pylori (Helisal rapid blood, Cortecs diagnostics, UK) and open-access endoscopy if positive Over 50 years: initial open access endoscopy Controls: prescribi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Dyspeptic patients 2. Aged 18 years and over (either sex) 3. Helicobacter pylori positive

Exclusion criteria

Exclusion criteria: 1. Previous endoscopy 2. Positive barium meal examination in the past three years 3. Unable to give informed consent 4. Unfit for endoscopy

Design outcomes

Primary

Measure	Time frame
Cost-effectiveness based on symptomatic improvement and health resource utilisation for dyspepsia at 12 months.	—

Secondary

Measure	Time frame
1. Quality of life (QoL) 2. Patient satisfaction	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026