Neonatal diseases Neonatal Diseases
Conditions
Interventions
This will be a randomised controlled trial with parallel group comparison. Babies will be allocated to either a nasal or an oral intubation group (via a sealed envelope). It is planned that those babi
Sponsors
Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Eligibility
Inclusion criteria
Inclusion criteria: Babies will be eligible for the research if they are: born between 25 and 40+6 weeks gestation, booked within the NHS trust, or transferred to the trust ex utero within the first seven days of life and require ventilatory support.
Exclusion criteria
Exclusion criteria: Babies will be excluded if they have significant congenital abnormalities, require surgical intervention, have significant neurological anomalies (i.e., Grade III IVH or higher, or any evidence of fitting), or if they only require mechanical ventilation for 24 hours or less.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Comparison of weaning onto full oral feeding in nasally intubated vs orally intubated babies 2. Time taken until first oral feed attempted, time taken until first oral feed completed 3. Time taken until 85% feeds are taken orally 4. Length of inpatient stay 5. Weight gain 6. Number of failed procedures, number of tube changes and the reason for change | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed