Presbyphonia Ear, Nose and Throat
Conditions
Interventions
This cross-sectional observational study is the first phase of a multiphase project to design and test the feasibility of a novel combined laryngeal and respiratory-focused treatment for presbyphonia.
Sponsors
University College London Hospitals NHS Foundation Trust
Eligibility
Sex/Gender
All
Age
50 Years to 110 Years
Inclusion criteria
Inclusion criteria: 1. 50 years of age or older 2. Ear, nose and throat (ENT) consultant-confirmed diagnosis of presbyphonia 3. Laryngeal images available for analysis 4. Typical hearing (as indicated by hearing screening at 40 dB HL at 500, 1000 and 1500Hz, bilaterally). 5. Willing and able to offer informed consent
Exclusion criteria
Exclusion criteria: 1. Recent (< 12 months) voice therapy 2. Diagnosis of a neurological condition affecting laryngeal or respiratory function (i.e. Parkinson’s disease, CVA, spasmodic dysphonia) 3. Diagnosis of additional laryngeal pathology 4. Contraindicated for spirometry 5. Failing cognitive screen (< 23 on the Rowland Universal Dementia Assessment Scale, RUDAS)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung volume initiation relative to end-expiratory level (LVI-R) measured in % of vital capacity (%VC) for reading and extemporaneous speech in comfortable and loud conditions measured using inductive respiratory plethysmography collected once during the research visit | — |
Secondary
| Measure | Time frame |
|---|---|
| The following secondary outcome measures will be collected during the research visit: 1. Lung volume termination relative to end-expiratory level (LVT-R) measured in % of vital capacity (%VC) for reading and extemporaneous speech in comfortable and loud conditions using inductive respiratory plethysmography 2. Lung volume excursion in %VC for reading and extemporaneous speech in comfortable and loud conditions measured using inductive respiratory plethysmography 3. Vital capacity expended per syllable (%VC/syl) for reading and extemporaneous speech in comfortable and loud conditions measured using inductive respiratory plethysmography 4. Ribcage contribution to lung volume excursion (in %) for reading and extemporaneous speech in comfortable and loud conditions measured using inductive respiratory plethysmography 5. Rate of speech (in syllables/second) for reading and extemporaneous speech in comfortable and loud conditions measured using acoustic signal and voice-to-text recognition algorithms 6. Utterance length (in syllables) for reading and extemporaneous speech in comfortable and loud conditions measured using acoustic signal and voice-to-text recognition algorithms 7. Vital capacity (in litres) measured using office-based spirometry 8. Forced vital capacity (in litres), FVC, measured using office-based spirometry once during the research visit 9. Peak expiratory flow (in litres/second), PEF, measured using office-based spirometry once during the research visit 10. Forced volume in one second (in litres), FEV1, measured using office-based spirometry once during the research visit 11. Maximum expiratory pressure (in cmH2O) measured using an office-based respiratory muscle strength assessment device 12. Maximum inspiratory pressure (in cmH2O) measured using an office-based respiratory muscle strength assessment device 13. Laryngeal resistance (in cmH2O/l/s) measured using phonatory aerodynamic assessment equipment once during the research visit 14. Acoustic voice | — |
Countries
England, United Kingdom
Contacts
Public ContactBrian Saccente-Kennedy
Outcome results
None listed