Assessment of dietary zinc intake and molecular biomarkers of zinc status in UK women

Assessment of dietary zinc intake and molecular biomarkers of zinc status in UK women: a double-blinded randomised case-controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN34559863

Enrollment

Registered

2013-09-19

Start date

2011-05-01

Completion date

Unknown

Last updated

2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Zinc deficiency Nutritional, Metabolic, Endocrine

Interventions

There are two dietary groups: vegetarian and non-vegetarian. There are two treatment-sub-groups: 1. 15 mg/day of zinc as zinc gluconate 2. Placebo Total duration of intervention: 2 weeks Route of adm

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Healthy females 2. British residents 3. Aged between 19-45 years

Exclusion criteria

Exclusion criteria: 1. Pregnant or breastfeeding now or in last 6 months 2. History of alcohol abuse 3. Current of recent (last 2 months) use of vitamin, mineral supplements 4. History of eating disorder 5. Consumption of meat, poultry or fish in the last year (for vegetarian group) 6. Recent traumas or surgery

Design outcomes

Primary

Measure	Time frame
1. Zinc transporter (SLC30A1 and SLC39A3) transcript levels in blood and saliva. 2. Serum concentrations of zinc by blood samples	—

Secondary

Measure	Time frame
Dietary intakes of zinc, phytate and other nutrients. Zinc supplementation was measured by blood and saliva.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026