A randomized trial comparing cyclosporine versus azathioprine for maintenance therapy in diffuse lupus nephritis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN34265870

Enrollment

Registered

2004-11-22

Start date

2000-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lupus nephritis Musculoskeletal Diseases Lupus nephritis

Interventions

Administration of 3 intravenous methylprednisolone pulses followed by a 2-3 month treatment with prednisone and oral cyclophosphamide. Patients with serum creatinine =1.5 mg/dl, proteinuria =0.5 g per

Eligibility

Inclusion criteria

Inclusion criteria: Seventy five patients presenting with diffuse proliferative lupus nephritis

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Not provided at time of registration	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026