Sparing confirmatory testing in primary aldosteronism: the combination of renin, aldosterone and potassium levels

Sparing Confirmatory Testing In Primary Aldosteronism (SCIPA): A Multicenter Retrospective Diagnostic Accuracy Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN34186253

Enrollment

157

Registered

2023-08-16

Start date

2010-01-01

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary aldosteronism Nutritional, Metabolic, Endocrine

Interventions

Baseline clinical and laboratory data will be retrieved from eligible patients who underwent saline suppression testing via the electronic medical records. The saline suppression test will serve as th

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Current inclusion criteria as of 21/06/2024: Patients above 18 years of age who underwent saline infusion test between January 2010 and March 2024 will be included in this study. Previous inclusion criteria: Patients above 18 years of age who underwent saline infusion test between January 2010 and July 2023 will be included in this study.

Exclusion criteria

Exclusion criteria: Those who did not complete the saline infusion test or did not comply with the saline infusion protocol will be excluded

Design outcomes

Primary

Measure	Time frame
Aldosterone elevation, plasma renin activity, and hypokalemia obtained at baseline (“screening values’) through electronic health records.	—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

Philippines

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026