Comparison of organs at risk and target volumes using MRI and CT scan in head and neck malignancy radiation treatment planning

Comparison of magnetic resonance imaging and CT scan based delineation of target volumes and organs at risk in the radiation treatment planning of head and neck malignancies

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN34023049

Enrollment

Registered

2022-04-07

Start date

2020-01-02

Completion date

Unknown

Last updated

2022-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Newly diagnosed biopsy-proven head and neck malignancy Cancer

Interventions

Pre-treatment staging and workup: Detailed clinical history and physical examination, biopsy from the lesion, complete haemogram, liver function test, kidney function test, chest x-ray

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Newly diagnosed biopsy-proven head and neck cancer 2. Age over 18 years 3. Eastern Co-operative Oncology Group (ECOG) performance status of 0- 2 4. Normal kidney function test

Exclusion criteria

Exclusion criteria: 1. Poor performance status of ECOG 3-4 2. Deranged serum creatinine and blood urea 3. Presence of metal elements in patient’s body that are MRI incompatible 4. Allergy to CT or MRI contrast 5. Second primary/recurrent head and neck cancer 6. Patients who have undergone tracheostomy

Design outcomes

Primary

Measure	Time frame
Concordance in CT and MRI contouring of target volumes and organs at risk, measured using the Dice Similarity Coeffcient, Conformity Index, Sensitivity Index, and Inclusion Index, calculated at the time of contouring	—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

India

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026