A double-blind randomised placebo-controlled trial of symptom-triggered alcohol detoxification on a general psychiatric ward

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN33971222

Enrollment

Registered

2004-09-30

Start date

2003-04-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and Behavioural Disorders: Alcohol dependence Mental and Behavioural Disorders Mental and behavioural disorders due to use of alcohol

Interventions

Double blind randomised control trial of two methods of alcohol detoxification. Randomised to 'symptom-triggered alcohol detoxification' or detoxification according to 'usual clinical practice'.

Eligibility

Inclusion criteria

Inclusion criteria: 70 patients admitted to one ward and who are identified by staff as requiring alcohol detoxification at the point of admission, and who meet International Statistical Classification of Diseases and Related Health Problems - tenth revision (ICD10) criteria for alcohol dependency.

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
1. Description of demographics: means, confidence intervals, medians, ranges. 2. Duration of detoxification: means, confidence intervals, t-tests. 3. Rates of completion of detoxification: percentages, chi-square. 4. Intensity of withdrawal symptoms: repeated measures analysis of variance (ANOVA). 5. Overall patient satisfaction: means, t-test. 6. Occurrence of complications of withdrawal: qualitative analysis for physical complications; repeated measures ANOVA for psychiatric symptoms. 7. Total medication used: means, t-tests. 8. Prognostic indicators for various outcomes: ANOVA, analysis of covariance (ANCOVA), linear and logistic regressions.	—

Measure

Time frame

1. Description of demographics: means, confidence intervals, medians, ranges. 2. Duration of detoxification: means, confidence intervals, t-tests. 3. Rates of completion of detoxification: percentages, chi-square. 4. Intensity of withdrawal symptoms: repeated measures analysis of variance (ANOVA). 5. Overall patient satisfaction: means, t-test. 6. Occurrence of complications of withdrawal: qualitative analysis for physical complications; repeated measures ANOVA for psychiatric symptoms. 7. Total medication used: means, t-tests. 8. Prognostic indicators for various outcomes: ANOVA, analysis of covariance (ANCOVA), linear and logistic regressions.

—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026