Subcutaneous oxyntomodulin reduces body-weight in overweight subjects

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN33638415

Enrollment

Registered

2005-07-22

Start date

2004-01-02

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity Nutritional, Metabolic, Endocrine Obesity

Interventions

Healthy overweight volunteers self-administered either saline or oxyntomodulin subcutaneously for four weeks, three times daily, 30 minutes before each meal, in a randomised double-blind parallel-grou

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy male and female volunteers, aged 18 to 55 years 2. A stable Body Mass Index (BMI) between 25 and 40 kg/m^2

Exclusion criteria

Exclusion criteria: 1. Abnormal eating behaviour 2. A current medical condition 3. Abnormal ElectroCardioGram (ECG) 4. Abnormal blood tests 5. Pregnancy or breast-feeding 6. Blood donation or participation in another research study within the last three months

Design outcomes

Primary

Measure	Time frame
Body weight, energy intake and adipose hormones.	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026