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Contingency intervention for reduction of cannabis in early psychosis

Randomised controlled trial of the clinical and cost-effectiveness of a contingency management intervention for reduction of cannabis use and of relapse in early psychosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN33576045
Enrollment
544
Registered
2011-11-28
Start date
2012-06-01
Completion date
Unknown
Last updated
2019-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychotic illnesses including schizophrenia, schizo-affective disorder and bipolar disorder with psychotic symptoms Mental and Behavioural Disorders Mental and behavioural disorders due to use of cannabinoids

Interventions

Experimental group: Contingency management involving voucher rewards for abstinence demonstrated by urinalysis together with psychoeducation delivered by care coordinators. Control gr

Sponsors

University College London (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Under the care of an early intervention service for psychosis 2. Diagnostic criteria for EIS entry require a first psychotic episode significantly impairing functioning and lasting more than a week 3. Problematic cannabis use is operationalised as having used cannabis at least once in at least 12 of the previous 24 weeks 4. Aged 18-39, male and female participants

Exclusion criteria

Exclusion criteria: Insufficient English to complete the study assessments

Design outcomes

Primary

MeasureTime frame
Time to relapse is assessed as admission to acute mental health care over 18 months

Secondary

MeasureTime frame
1. Presence of cannabis on urinalysis at 3 months and at 18 months of follow up 2. Positive symptom severity measured by Positive and Negative Syndrome Scale (PANSS) at 3 months and 18 months 3. Engagement in work or study is assessed by participant self report at 3 months and 18 months

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 12, 2026