Skip to content

Addressing the challenges associated with neglected infectious diseases in at-risk individuals

Metabolic and molecular ecological evolution of opportunistic pulmonary fungal co-infections

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN33572982
Enrollment
480
Registered
2021-11-17
Start date
2021-10-10
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary fungal co-infections in patients with TB-like symptoms Infections and Infestations

Interventions

Participants earmarked for the study will be consented to, instructed and guided on the sputum sample collection. Up to three samples will be collected from each participant with a space of 3-4 days.

Sponsors

Mbarara University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. HIV/AIDS patients suspected of TB 2. Presenting with TB-like symptoms including a chronic cough that has persisted for more than 3 months 3. Aged 18 years and above 4. TB naive 5. Give consent

Exclusion criteria

Exclusion criteria: 1. Critically ill patients, who would delay recruitment due to associated delays in sample collection and consent 2. Diabetics and pregnant women suspected of TB are managed differently according to TB guidelines 3. HIV/AIDs patients with TB-like symptoms but on anti-TB treatment 4. Patients with a known diagnosis

Design outcomes

Primary

MeasureTime frame
Incidence of pulmonary fungal infections measured using Prevalence Index at baseline and 18, 30 and 36 months

Secondary

MeasureTime frame
Clinical management measured using a diagnostic approach at baseline and 36 months

Countries

Uganda

Contacts

Public ContactHerbert Itabangi
hitabangi@gmail.com+256 (0)775554564

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 9, 2026