A multicentre randomised controlled trial of transabdominal versus transvaginal cervical cerclage

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN33404560

Enrollment

129

Registered

2008-09-26

Start date

2008-01-01

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm birth - prevention Pregnancy and Childbirth Preterm labour

Interventions

The participants will be randomly allocated to the following three arms: 1. Low vaginal cervical cerclage 2. High vaginal cervical cerclage 3. Transabdo

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Previous second trimester miscarriage or preterm birth before 28 weeks' gestation despite having a low vaginal cerclage in place 2. Not yet pregnant or <14 weeks' pregnant

Exclusion criteria

Exclusion criteria: 1. Inability or unwillingness to give informed consent 2. Women under the age of 16

Design outcomes

Primary

Measure	Time frame
1. Rate of delivery <32 weeks' gestation 2. Rate of neonatal death	—

Secondary

Measure	Time frame
1. Serious operative complication rates 2. Complications of pre- and post-conception cerclages for high vaginal cerclages and transabdominal cerclages Duration of follow up: a maximum of 2 years	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026