Undernourished older people admitted with an acute illness Nutritional, Metabolic, Endocrine Nutritional supplementation
Conditions
Interventions
Complete liquid protein and energy supplement (400 ml/day) or matching liquid placebo with minimal protein and energy content over a 12 week period.
Sponsors
University of Dundee (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 70 years and over 2. Community dwelling 3. Admitted to hospital with an acute illness 4. Body mass index =24 kg/m^2 5. Mid-arm muscle circumference below the 10th centile and/or weight loss of 5% or more during hospital stay
Exclusion criteria
Exclusion criteria: 1. Chronic liver diease or renal failure 2. Nursing home residents 3. Cognitive impairment precluding informed consent 4. Dysphagia 5. Metastatic carcinoma or other terminal illness 6. Pathology such as inflammatory arthritis or stroke affecting non-dominant handgrip 7. Major surgery within one month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Changes in muscle strength (handgrip dynamometry) 2. Changes in disability (Barthel index) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Changes in lower limb muscle strength 2. Changes in weight 3. Changes in dietary intake (24 hour dietary recall) 4. Changes in daily physical activity levels (accelerometry) 5. Changes in health related quality of life (Euroquol) 6. Unplanned hospital readmissions | — |
Countries
United Kingdom
Outcome results
None listed