Should we replace the back of the knee cap all of the time or some of the time in patients having knee replacement surgery? A trial comparing patient outcomes and the cost to the NHS.

The clinical and cost-effectiveness of elective primary total knee replacement with PAtellar Resurfacing compared to selective patellar resurfacing. A pragmatic multicentre randomised controlled Trial with blinding (PART)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN33276681

Enrollment

530

Registered

2023-02-27

Start date

2023-04-17

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total knee replacement with patellar resurfacing compared to selective patellar resurfacing Musculoskeletal Diseases

Interventions

Randomisation: Randomisation will be carried out intraoperatively once total knee replacement has been performed and the size of the patella can be measured. Participants will be allocated in a 1:1 ra

Eligibility

Sex/Gender

All

Age

18 Years to 120 Years

Inclusion criteria

Inclusion criteria: 1. 18 years of age or older 2. Elective primary Total Knee Replacement (TKR) for primary Osteoarthritis (OA) 3. Resident of England (English postcode) and surgery in an NHS England hospital

Exclusion criteria

Exclusion criteria: 1. Revision TKR 2. Unicompartmental knee replacement 3. Primary TKR with: 3.1. need for constrained implants (e.g., constrained condylar or hinge), 3.2. isolated patellofemoral OA, 3.3. history of septic arthritis, 3.4. diagnosis other than primary OA 4. Intra-operative patellar thickness insufficient for safe patellar resurfacing as determined by the treating surgeon (patellar thickness will be recorded in the case report forms for monitoring purposes) 5. Patient unable/unwilling to adhere to trial procedures 6. Patient unable to provide written informed consent. 7. Participating in another study that may affect the outcomes of this trial or that does not permit co-enrolment in another study or where co-enrolment would be burdensome to the patient. This will be assessed on a case-by-case basis by the local PI, in consultation with the co-CIs.

Design outcomes

Primary

Measure	Time frame
Oxford Knee Score (OKS) questionnaire 1 year after randomisation	—

Secondary

Measure	Time frame
Patient reported questionnaires at 3 months, 6 months and 1 year post randomisation: 1. Oxford Knee Score 2. Knee Injury & Osteoarthritis Outcome Score 3. EQ-5D-5L Quality of health questionnaire Resource data will be collected at 3 months, 6 months and 1 year post randomisation, specifically: 4. Postoperative complications 5. Need for further surgery 6. Further patella resurfacing surgery 7. Resource use and costs within 1 year 8. Mortality data	—

Measure

Time frame

Patient reported questionnaires at 3 months, 6 months and 1 year post randomisation: 1. Oxford Knee Score 2. Knee Injury & Osteoarthritis Outcome Score 3. EQ-5D-5L Quality of health questionnaire Resource data will be collected at 3 months, 6 months and 1 year post randomisation, specifically: 4. Postoperative complications 5. Need for further surgery 6. Further patella resurfacing surgery 7. Resource use and costs within 1 year 8. Mortality data

—

Countries

England, United Kingdom

Contacts

Public ContactAdam Boon

PART-trial@bristol.ac.uk-

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jun 11, 2026