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Variation of radiotherapy target volume definition, dose to organs at risk (OAR) and clinical target volumes using anatomic (CT) versus combined anatomic and molecular imaging (PET-CT): Intensity Modulated Radiotherapy delivered using a Tomotherapy Hi Art machine

Variation of radiotherapy target volume definition, dose to organs at risk (OAR) and clinical target volumes using anatomic (CT) versus combined anatomic and molecular imaging (PET-CT): Intensity Modulated Radiotherapy delivered using a Tomotherapy Hi Art machine

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN33175361
Enrollment
30
Registered
2010-04-29
Start date
2009-05-01
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: National Cancer Research Network

Interventions

Standard pre-radiotherapy planning imaging is with a contrast enhanced CT scan. In the study all patients were required to have a 18 FDG PET-CT scan in the treatment position. Study entry: registrati

Sponsors

Newcastle Hospitals NHS Foundation Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Tumours of oropharynx area in the head and neck 2. Have involved or uninvolved neck nodes 3. Being treated with tomotherapy IMRT 4. Either sex

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
To explore if the FDG PET CT based radiotherapy target volumes are different to that of CT scan—

Secondary

MeasureTime frame
Feasibility of dose escalation in tumour volumes in oropharyngeal SCC.—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026