Chronic obstructive pulmonary disease (COPD) Respiratory
Conditions
Interventions
This is an observational study. The aim of this study is to investigate the effects of an acute exacerbation of COPD on resolution physiology. This study is divided into a main study and a sub-study.
Sponsors
University of Leicester
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Participant is willing and able to give informed consent for participation in the study 2. Male or Female, aged 18 years old and above 3. Able (in the Investigator's opinion) and willing to comply with all the study requirements 4. Hospitalised following an acute exacerbation
Exclusion criteria
Exclusion criteria: 1. Female participants who are pregnant or lactating 2. Participant is unwilling or unable to give informed consent for participation 3. Unable (in the Investigators opinion) or unwilling to comply with the study requirements 4. Participants who are unable to understand written and spoken English. 5. Participant has any other significant disease or disorder which, in the opinion of the Investigator may either put the participants at risk, influence their ability to participate in the study or influence the result of the study. This includes but is not limited to - respiratory diseases such as asthma, bronchiectasis, pneumonia and cancer. 6. Patients that require intubation or admission to ICU.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Levels of specialised pro-resolving mediators (SPMs) measured using the Liquid Chromatography Mass Spectrometry (LCMS) in the baseline blood sample | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
England, United Kingdom
Contacts
Public ContactOluwadamilola Yinka-Adebisi
Outcome results
None listed