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Comparison of non-invasive positive pressure ventilation for extubated patients who fail a single spontaneous breathing trial vs conventional weaning

Comparison of non-invasive positive pressure ventilation for extubated patients who fail a single spontaneous breathing trial vs conventional weaning

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN32810409
Enrollment
90
Registered
2007-09-28
Start date
2006-03-13
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory: Positive pressure ventilation Respiratory Positive pressure ventilation

Interventions

Noninvasive positive pressure ventilation vs conventional weaning

Sponsors

Record Provided by the NHSTCT Register - 2007 Update - Department of Health
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients will need to meet the criteria for reducing breathing support - will not be weaned until physiologically ready. 2. Patients will have to be on a breathing machine attached to a tube in the mouth for at least 48 hours - patients who are on a breathing machine for 18 years - patient should be able to make own legal judgements to treatment 4. Written informed consent obtained - unethical to carry out study without consent 5. Failed an attempt to try breathing without help - study only being carried out on people who have difficulty with weaning

Exclusion criteria

Exclusion criteria: Added September 2008: 1. Patients who are generally not suitable for noninvasive ventilationGrade III/IV intubation 2. Gastric/oesophageal surgery on this admission 3. Patients who it has been decided would not be for re-intubation once extubated

Design outcomes

Primary

MeasureTime frame
Duration of time with breathing support tube in the mouth in days

Secondary

MeasureTime frame
Length of intensive care unit and hospital stay in days

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026