Patients suffering from hip osteoarthritis Musculoskeletal Diseases Coxarthrosis
Conditions
Interventions
Ultrasound-guided intra-articular injections of hyaluronic acid (MW 1500-2000 KDa)
Injections were performed at least every 6 months, but some patients were treated as often as every 3 months.
The st
Sponsors
Fidia Farmaceutici S.p.A (Italy)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age > 40 years 2. Hip OA with joint pain of at least one year?s duration 2.1. Symptomatic hip OA according to the American College of Rheumatology (ACR) 2.2. Grade I, II, III or IV hip OA according to the Kellgren-Lawrence classification 2.3. Evaluated on an X-ray taken no more than two months before enrolment
Exclusion criteria
Exclusion criteria: 1. Concomitant use of oral anticoagulant therapy 2. Severe reduction of joint space narrowing evident on X-ray 3. Significant co-morbidities, hypersensitivity to HA or to avian proteins 4. Chronic systemic steroid treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes from baseline to the final visit with respect to Lequesne index | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Changes from baseline to the final visit with respect to 1.1. Visual Analogue Scale (VAS) 1.2. Non-steroidal anti-inflammatory drug (NSAID) intake 2. Assessment of predictive indices for the response variables (lequesne and VAS indexes) | — |
Countries
Italy
Outcome results
None listed