Laryngeal cancer screening Cancer Malignant neoplasm of larynx
Conditions
Interventions
Clinical recruitment of up to 40 patients for in vivo study shall occur initially at a single site (Northwick Park ENT-Head & Neck Department). Patients attending the outpatient service for secondary
Sponsors
North West London Hospitals NHS Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. All patients over the age of 18 years (no upper age limit) 2. Male or female gender 3. Patients able to provide informed consent to OCT-adapted flexible nasendoscope examination under topical local anaesthesia and completing a patient experience questionnaire provided at the end of procedure 4. Smokers and non-smokers
Exclusion criteria
Exclusion criteria: 1. All patients under the age of 18 years 2. All patients from whom informed consent has not been obtained prior to tissue resection or OCT-adapted flexible nasendoscopy respectively
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Characterisation & correlation of mucosal pathology (OCT images vs Histopathology) following direct microlaryngoscopy and biopsy of laryngeal lesion under general anaesthesia (GA) | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Experience Questionnaire at initial out-patient visit , immediately following nasendoscopy examination and image capture under LA | — |
Countries
United Kingdom
Outcome results
None listed