Tooth whitening Oral Health Tooth whitening
Conditions
Interventions
1. Treatment with whitening kits with 10% carbamide peroxide
2. Treatment with whitening kits with 16% carbamide peroxide
3. Treatment with whitening kits with 22% carbamide peroxide
4. Treatment w
Sponsors
Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Healthy volunteers (aged 19- 53 years, either sex)
Exclusion criteria
Exclusion criteria: 1. Pregnant or breast-feeding women 2. Absence of systemic diseases, periodontal problems or any kind of medication or prosthesis in the regions assigned for the brush biopsy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current information as of 26/01/2009: Alteration in tooth colour from the three prescribed agents (non-active placebo, 10% carbamide peroxide and 16% carbamide peroxide) during a 2 week course of tooth whitening and the overall colour stability at 3 months. Initial information at time of registration: 1. To measure the efficacy of carbamide peroxide concentration on rate and longevity of tooth shade variation 2. To investigate the effect of currently used dosages of carbamide peroxide on human oral epithelium | — |
Secondary
| Measure | Time frame |
|---|---|
| Added 26/01/2009: 1. Soft tissue changes during the active treatment period and on subsequent review 2. Tooth senstivitiy over the active treatment period 3. Patients perceptions of tooth colour at baseline, 2 weeks and 3 months | — |
Countries
United Kingdom
Outcome results
None listed