Clinical Assessment Study of the Foot

An observational cohort study to investigate the long-term course of foot pain and foot osteoarthritis in community-dwelling adults aged 50 years and over

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN32588605

Enrollment

5000

Registered

2011-09-22

Start date

2010-05-15

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Foot pain, foot osteoarthritis Musculoskeletal Diseases Other arthrosis

Interventions

The Clinical Assessment Study of the Foot (CASF) is a prospective cohort study which is interested in community-dwelling adults aged 50 years and older with self-reported foot pain. Its main objective

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Population survey: 1. Registered with one of the four participating local general practices 2. Age 50 years and over at the time of baseline survey, either sex Invitation to attend for clinical assessment: 1. Responded to baseline Health Survey questionnaire 2. Male and female, lower age limit of 50 years 3. Self-reported foot pain in the previous 12 months 4. Provided written informed consent to further contact

Exclusion criteria

Exclusion criteria: Vulnerable groups (e.g. significant cognitive impairment, learning difficulties)

Design outcomes

Primary

Measure	Time frame
Manchester Foot Pain and Disability Index, measured at baseline, 18 months and 3 years	—

Secondary

Measure	Time frame
1. Radiographic foot OA 2. Radiographic hand OA 3. Foot pain persistence 4. Chronic Pain Grade 5. General health (12-iterm short form health survey [SF-12]) 6. Current employment status 7. Anxiety and depression (Hospital Anxiety and Depression questionnaire [HAD]) 8. Pain location 9. Symptom satisfaction 10. Presence of hand pain and problems 11. Nodes and swelling 12. Participation restriction 13. Secondary care referral 14. Joint replacement surgery These will be collected at baseline, 18 month follow-up and 3 year follow-up.	—

Measure

Time frame

1. Radiographic foot OA 2. Radiographic hand OA 3. Foot pain persistence 4. Chronic Pain Grade 5. General health (12-iterm short form health survey [SF-12]) 6. Current employment status 7. Anxiety and depression (Hospital Anxiety and Depression questionnaire [HAD]) 8. Pain location 9. Symptom satisfaction 10. Presence of hand pain and problems 11. Nodes and swelling 12. Participation restriction 13. Secondary care referral 14. Joint replacement surgery These will be collected at baseline, 18 month follow-up and 3 year follow-up.

—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026