One size does not fit all: is whole-body computed tomography beneficial for all patients with suspected major trauma?

One size does not fit all: is whole-body computed tomography beneficial for all patients with suspected major trauma? A prospective randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN32471051

Enrollment

486

Registered

2025-11-05

Start date

2011-05-02

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major trauma Injury, Occupational Diseases, Poisoning

Interventions

This study randomly assigned trauma patients to either a WBCT (whole-body CT) group or a conventional imaging group. All patients who met the selection criteria were referred to a randomization sheet.

Eligibility

Sex/Gender

All

Age

16 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients admitted directly to our emergency department (ED) who met the trauma team activation criteria were considered candidates for major or multiple traumas. The criteria included one or more of the following: 1. Unstable vital signs: 1.1. Systolic blood pressure 29 or 6 meters 3.2. Pedestrian struck by a vehicle 3.3. Heavy object crush injury 3.4. Ejection from a vehicle 3.5. Death of another passenger in the same event 3.6. Extreme age (65 years) in cases of multiple trauma

Exclusion criteria

Exclusion criteria: 1. Under 16 years of age 2. Pregnant 3. Referrals from other hospitals 4 .Suspected of drowning 5. Experiencing traumatic cardiac arrest (TCA) without return of spontaneous circulation (ROSC) 6. Solitary burn injuries 7. Clearly isolated focal injuries

Design outcomes

Primary

Measure	Time frame
1. Pre-hospital time: time from the accident to the patient’s arrival at the ER 2. Resuscitation time: time from arrival at the ER to the completion of the primary survey and life-saving procedures 3. Complete primary imaging time: time from arrival to the completion of the first-line imaging study in each group 4. Final decision-making time: interval between arrival and disposition decision 5. Total ER stay time: total time from arrival to discharge from the ER 6. Complications, defined as in-hospital deterioration of organ function compared to the status at the time of the initial ED assessment 7. Diagnostic delays, defined as cases where additional diagnoses were made after admission or discharge that differed from the original diagnoses made in the ED, indicating a missed diagnosis	—

Measure

Time frame

1. Pre-hospital time: time from the accident to the patient’s arrival at the ER 2. Resuscitation time: time from arrival at the ER to the completion of the primary survey and life-saving procedures 3. Complete primary imaging time: time from arrival to the completion of the first-line imaging study in each group 4. Final decision-making time: interval between arrival and disposition decision 5. Total ER stay time: total time from arrival to discharge from the ER 6. Complications, defined as in-hospital deterioration of organ function compared to the status at the time of the initial ED assessment 7. Diagnostic delays, defined as cases where additional diagnoses were made after admission or discharge that differed from the original diagnoses made in the ED, indicating a missed diagnosis

—

Secondary

Measure	Time frame
Subgroup analyses comparison: Unstable, Unconscious, and Mechanism-related groups	—

Countries

Taiwan

Contacts

Public ContactI-Ming Kuo

m7017@cgmh.org.tw+886 (0)2 22630588 ext 6262

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026