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Cognitive remediation therapy in bipolar disorder

The Cognitive Remediation in Bipolar (CRiB) Study: a feasibility trial of cognitive remediation therapy in people with bipolar disorder versus treatment as usual

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN32290525
Enrollment
60
Registered
2016-02-03
Start date
2016-02-10
Completion date
Unknown
Last updated
2023-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Mental Health

Interventions

Participants are randomly allocated to one of two groups. Intervention group: Intervention group: Participants receive cognitive remediation therapy (CRT) alongside their usual treatm

Sponsors

King's College London (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years 2. Confirmed DSM­V diagnosis of bipolar I disorder 3. Those who have been in an euthymic state at two timepoints one week apart, defined by scores of <8 on the Hamilton Rating Scale for Depression and Young Mania Rating Scale at both timepoints

Exclusion criteria

Exclusion criteria: 1. Presence of a substantial neurological/neurodevelopmental disorder 2. Current diagnosis of personality disorder 3. Recent involvement with alcohol or substance abuse 4. Aged under 18 or over 65 years old 5. Severe visual or auditory problems 6. Unable to understand verbal and written instructions in English

Design outcomes

Secondary

MeasureTime frame
1. Engagement with the intervention is determined at 12 weeks 2. Level of functioning is measured at baseline 12 and 24 weeks 3. Symptom prevention is measured at baseline 12 and 24 weeks

Primary

MeasureTime frame
Cognitive Performance is measured at baseline, 12 and 24 weeks.

Countries

England, United Kingdom

Contacts

Public ContactBecci Strawbridge
becci.strawbridge@kcl.ac.uk+44 (0)207 848 5305

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 1, 2026