Baclofen for maintenance treatment of opioid dependence: A randomised double-blind placebo-controlled clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN32121581

Enrollment

Registered

2003-11-17

Start date

2001-11-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid dependence Mental and Behavioural Disorders Drug addiction

Interventions

A total of 40 opioid-dependent patients were detoxified and randomly assigned to receive baclofen (20 mg three times a day [t.i.d.]) or placebo (in identical-appearing tablets t.i.d.) in a 12-week, do

Eligibility

Inclusion criteria

Inclusion criteria: Subjects were eligible for the study if they: 1. Met DSM-IV criteria for opioid dependence 2. Were detoxified at our addiction clinic 3. Were between 18 and 60 years of age 4. Gave written informed consent for participation in the study Opioid dependence (according to Diagnostic and Statistical Manual of Mental Disorders, fourth edition [DSM-IV] criteria).

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Not provided at time of registration	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

Iran

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 13, 2026