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Effect of prophylactic Brimonidine instillation on bleeding during Strabismus surgery in adults

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN31792393
Enrollment
90
Registered
2007-04-13
Start date
2004-01-10
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strabismus Eye Diseases Strabismus

Interventions

Patients were instilled with either a single drop of brimonidine-purite 0.15%, phenylephrine 1% or sodium hyaluronate 0.1% 15 minutes prior to strabismus surgery.

Sponsors

Yonsei University College of Medicine (South Korea)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients who underwent strabismus surgery under topical anaesthesia.

Exclusion criteria

Exclusion criteria: Patients who had received prior ocular surgery were excluded.

Design outcomes

Primary

MeasureTime frame
Intraoperative bleeding and postoperative subconjunctival haemorrhage were graded on a scale of one to three. Intraoperative bleeding was scored during the surgery, postoperative subconjunctival haemorrhage was graded four hours after surgery.

Secondary

MeasureTime frame
Cardiovascular complications and angle-closure glaucoma attack were reported during all follow up periods.

Countries

Korea, South

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026