Comparison of lidocaine spray 10% vs. lidocaine gel 2% for preventing post-intubation and post-extubation complications

Comparison of the use of lidocaine spray vs lidocaine gel for post-intubation and post-extubation complications

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN31659103

Enrollment

Registered

2025-02-01

Start date

2024-12-15

Completion date

Unknown

Last updated

2025-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective surgery patients Surgery

Interventions

This study is an experimental analytical research with a randomized controlled trial (RCT) design aimed at comparing the effectiveness of 10% Lidocaine Spray and 2% Lidocaine Gel in managing post-intu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients undergoing surgery 2. General Anesthesia and Endotracheal Tube (GA-ETT) 3. Aged between 18 and 64 years 4. Classified as ASA (American Society of Anesthesiologists) I or II 5. Surgeries lasting less than 2 hours

Exclusion criteria

Exclusion criteria: Patients predicted to encounter intubation difficulties

Design outcomes

Primary

Measure	Time frame
1. Diastolic Blood Pressure is measured using Non-invasive Blood Pressure at baseline, 2 hours, and 24 hours post-surgery 2. Systolic Blood Pressure is measured using Non-invasive Blood Pressure at baseline, 2 hours, and 24 hours post-surgery 3. Heart rate (Pulse) is measured using monitor at baseline, 2 hours, and 24 hours post-surgery 4. Postoperative Sore Throat (POST) is measured using Post Scoring at baseline, 2 hours, and 24 hours post-surgery 5. Post-extubation complication are assessed using vital signs assessment by monitor (Systolic and diastolic blood pressure, patient’s heart rate) at baseline, 2 hours, and 24 hours post-surgery	—

Measure

Time frame

1. Diastolic Blood Pressure is measured using Non-invasive Blood Pressure at baseline, 2 hours, and 24 hours post-surgery 2. Systolic Blood Pressure is measured using Non-invasive Blood Pressure at baseline, 2 hours, and 24 hours post-surgery 3. Heart rate (Pulse) is measured using monitor at baseline, 2 hours, and 24 hours post-surgery 4. Postoperative Sore Throat (POST) is measured using Post Scoring at baseline, 2 hours, and 24 hours post-surgery 5. Post-extubation complication are assessed using vital signs assessment by monitor (Systolic and diastolic blood pressure, patient’s heart rate) at baseline, 2 hours, and 24 hours post-surgery

—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

Indonesia

Contacts

Public ContactAndriamuri Lubis

andriamuri@usu.ac.id+62 08126078194

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026