Overweight and obesity in women Nutritional, Metabolic, Endocrine Overweight and obesity in women
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 20-45 years 2. Female 3. Stable weight for the last 2 months 4. Body mass index (BMI) >30 kg/m² 5. Sedentary (no more than 2 hours of structured physical activity per week) 6. Menstrual periods every month
Exclusion criteria
Exclusion criteria: 1. Pregnancy 2. Smokers 3. Drug users 4. Consuming more than 2 units of alcohol per day 5. Claustrophobic 6. Use of nutritional supplements 7. Not using oral contraceptives or hormones 8. Diabetic (type 1 or type 2) 9. Thyroid disorders 10. Renal disease 11. Liver disease 12. Cancer 13. Inflammatory disease 14. Asthma 15. Respiratory problems 16. Cardiovascular disease 17. Peripheral vascular disease 18. Stroke 19. Orthopaedic limitations 20. Using any of the following: 20.1. Systemic corticosteroids (e.g. prednisone) 20.2. Anti-obesity agents (e.g. Xenical®, Meridia®) 20.3. Natural supplemented for weight loss or weight control (e.g. Megace) 20.4. Antipsychotics 20.5. Mood stabilisers or antidepressants that have a significant impact on weight (e.g. Zyprexa®, Remeron®) 20.6. Diuretics (e.g. Lasix®, furosemide) 21. Treatment with thyroid hormones (stable dose for at least 3 months before the start of the study) 22. Use of thiazide diuretics (hydrochlotozide) for less than 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The following were assessed during 3 data collection phases - a 7 day baseline phase (1 month prior to the exercise intervention), a 14 day phase at the beginning of the intervention, and a 7 day phase at the end of the intervention (after 3 months): 1. Energy intake, assessed using lunch boxes and a food journal (according to McNeil et al., 2012) 2. Energy expenditure, assessed using doubly labelled water (according to Schoeller and van Santen, 1982). 3. Body composition, assessed using dual X-ray absorptiometry | — |
Secondary
| Measure | Time frame |
|---|---|
| The following were assessed during 3 data collection phases - a 7 day baseline phase (1 month prior to the exercise intervention), a 14 day phase at the beginning of the intervention, and a 7 day phase at the end of the intervention (after 3 months): 1. Appetite, assessed using a visual analogue scale (VAS) 2. Eating behaviour traits, assessed using the Three-Factor Eating Questionnaire (TFEQ) 3. Food rewards, assessed using the Leeds Food Preference Questionnaire (LFPQ) 4. Time spent performing activities, assessed using an accelerometer | — |
Countries
Canada