Prevention and treatment of carotid sinus reflex in patients undergoing carotid artery stenting Circulatory System
Conditions
Interventions
The randomization sequence will be generated by a statistician not involved in the trial using the random number table method. The allocation sequence will be concealed in sequentially numbered, seale
Sponsors
Beijing Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. European Society for Vascular Surgery (ESVS) 2023-defined carotid stenosis 2. CAS-indicated per Chinese Guidelines 2015 3. Willingness for endovascular intervention 4. Aged 18-75 years inclusive 5. Signed informed consent
Exclusion criteria
Exclusion criteria: 1. Presence of cardiac pacemaker 2. Documented severe dysfunction in any major organ system (cardiac, pulmonary, hepatic, or renal) 3. Identified coagulation disorders 4. Active skin infection at proposed acupuncture sites 5. Indication for emergency surgical intervention or additional neurointerventional procedures 6. Diagnosed psychiatric conditions or documented non-compliance that may compromise treatment protocol adherence 7. Documented intolerance to electroacupuncture therapy or history of severe adverse reactions 8. Anatomically unsuitable vascular access confirmed by imaging studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of carotid sinus reflex (CSR) incidence, calculated by comparing baseline blood pressure/heart rate with the lowest intraoperative and postoperative values recorded via continuous non-invasive monitoring and ECG during and after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of persistent carotid sinus reflex (CSR), measured using continuous hemodynamic monitoring data and anesthesia records intraoperatively and postoperatively until hospital discharge 2. Vasoactive drug utilization rate and postoperative pharmacological rescue rate: the percentage of patients requiring vasopressors/inotropes measured using anesthesia medication records and postoperative nursing charts during the procedure and postoperatively until discharge 3. Adverse event incidence rate: the frequency of complications (e.g., arrhythmias, stroke) measured using medical records and investigator-reported events from procedure initiation until hospital discharge 4. Neurological deficit measured using the NIH Stroke Scale (NIHSS) score at preoperative baseline (1 day before surgery), 1 hour postoperatively, 24 hours postoperatively, on the day of discharge, and 4 weeks post-discharge 5. Length of hospital stay: days from admission to discharge measured using hospital medical records at the time of discharge | — |
Countries
China
Contacts
Public ContactChuanjin Song
Outcome results
None listed