Periodontitis Oral Health Periodontitis
Conditions
Interventions
Participants are randomly allocated to one of two groups. Those in the intervention group receive a comprehensive 6 months dental scaling and root planning treatment program, as well as standard treat
Sponsors
Faculty of Dental Medicine Universitas Airlangga
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Children aged 6-16 years of any gender and ethnicity 2. Diagnosed with HDM allergies by positive skin-prick test 3. Diagnosed with gingivitis by >2 plaque index according to Silness-Löe criteria 4. High baseline IgE titer (>90 pg/ml), suggesting a positive childhood allergic potency 5. Understand and able to cooperate to the research protocol 6. Parents give voluntary, signed written consent in accordance with our institutional policies
Exclusion criteria
Exclusion criteria: 1. Taking any antihistamines or steroid which commonly interferes with results of skin-prick within one month 2. Previously experienced any immunotherapy procedures 3. Previously experienced dental scaling and root planning within 6 months 4. Presence of low grade fever due to infections rather than gingivitis 5. Recent blood disorders or congenital abnormalities 6. Any medical conditions that may be harmful if involved in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IgE is measured from a blood sample at baseline and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| IgG4 is measured from a blood sample at baseline and 6 months | — |
Countries
Indonesia
Outcome results
None listed