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Paralysis post stroke, rehabilitation therapy by immobilizing the normal upper arm

Motor rehabilitation: brain plasticity or neuronal regeneration?

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN31408782
Enrollment
40
Registered
2012-03-13
Start date
2010-06-30
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke motor deficit Circulatory System Stroke, not specified as haemorrhage or infarction

Interventions

Patients who meet inclusion criteria will undergo physical rehabilitation therapy consisting of immobilizing the upper healthy limb by means of a specially designed vest and forcing the affected upper
the rest of the day the patient will continue with his good arm immobilized. The immobilization of the arm should be removed at night. During this therapy a physiotherapist will be all the time forcin

Sponsors

Neurological Institute of Colombia (Colombia)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients of either gender without age limits 2. Presence of motor deficits due for stroke with hemiparesis or monoparesis 3. At least 3 years after the stroke 4. The affected arm should have at least traces of movement

Exclusion criteria

Exclusion criteria: 1. Presence of joint contractures 2. Lower motor neuron pathology 3. Pathology that compromises the neuromuscular junction 4. Spinal cord pathology 5. Inability to understand instructions and adhere to the intervention

Design outcomes

Primary

MeasureTime frame
1. Before and after constriction-induced therapy, the movement of the arm of patient are measured, taking into account the angle of movement at the level of fingers, wrist, elbow and shoulder, and also assessing the strength of these movements. 2. The movements of the arm and gait of the patient will be filmed before and after the therapy. Furthermore, patients will undergo a functional magnetic resonance imaging (fMRI) scan before and after the therapy. The comparison of the above parameters before and after treatment will measure the effectiveness of treatment.

Secondary

MeasureTime frame
Changes in motor cortex activity, assessed by fMRI, allow evaluation of the role of the cortical areas in the rehabilitation of the motor function by the therapy

Countries

Colombia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026