Systemic Lupus Erythematosus Musculoskeletal Diseases Systemic Lupus Erythematosus
Conditions
Interventions
Twelve Systemic lupus erythematosus participants and twelve age and gender matched controls will be recruited from Northern Ireland and donate a 27mls blood samples.
Peripheral blood mononuclear cell
Sponsors
Ulster University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Systemic lupus erythematosus (SLE) participants: 1. Aged between 18-65 2. A diagnosis of SLE (American College of Rheumatology criteria) 3. Not currently pregnant 4. Not currently taking any n-3 fatty acid supplements Control participants: 1. Aged between 18-65 2. Free from illness 3. Not taking any medication (including non-steroidal anti-inflammatories) 4. Not currently pregnant 5. Not currently taking any n-3 fatty acid supplements
Exclusion criteria
Exclusion criteria: Systemic lupus erythematosus (SLE) participants: 1. Currently on high dose steroids (>10mg daily) 2. Currently suffering from an acute illness 3. Regularly consume more than 3 portions of fish per week 4. Pregnancy 5. Currently taking any n-3 fatty acid supplements Control participants: 1. Regularly consume more than 3 portions of fish per week 2. Pregnancy 3. Currently taking any n-3 fatty acid supplements
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pro-inflammatory cytokines secreted from peripheral blood mononuclear cells will be measured using a multiplex ELISA assay. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome measures. | — |
Countries
United Kingdom
Outcome results
None listed