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Acceptability of treatment as prevention messages in Malawi

Developing “U=U” communication messages targeting HIV discordant couples in Malawi: Establishing evidence on feasibility and acceptability

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN31351715
Enrollment
250
Registered
2024-03-15
Start date
2024-05-14
Completion date
Unknown
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of HIV transmission in HIV-mixed status relationships through the provision of undetectable = untransmittable information Infections and Infestations

Interventions

As well as the care provided in the control arm, those in the intervention arm (n=25) will receive the “U=U” information via SMS and other pictorial, video, audio and written materials about the role

Sponsors

Kamuzu University of Health Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Antenatal care attendees in the second trimester 2. PLHIV (known or newly diagnosed) 3. 18 years or older 4. Primary male partner of unknown HIV status (last negative test >3 months/not known to be on ART) intending to remain in Blantyre for 6 months

Exclusion criteria

Exclusion criteria: 1. Unwilling or unable to provide informed consent; 2. Requires urgent medical attention or has severe mental health problems e.g. actively suicidal

Design outcomes

Primary

MeasureTime frame
1. Proportion of male partners of HIV-Positive ANC attendees who test for HIV within 28 days measured using self-report 2. Proportion of male partners testing for HIV within 28 days of receipt of “U=U” communication materials by the woman measured using self-report

Secondary

MeasureTime frame
1. Proportion of male partners who accept to participate in U=U sessions measured through attendance to sessions at 28 days - project records 2. Proportion of male partners reporting HIV prevention approaches measured at 28 days using project records 3. Number of HIV-related intimate partner violence or gender-based violence measured using self-report at 28 days

Countries

Malawi

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026