Effects of increased egg consumption as part of a weight-reducing diet on blood cholesterol and related biomarkers of coronary heart disease risk

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN31221145

Enrollment

Registered

2005-10-05

Start date

2005-05-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight Nutritional, Metabolic, Endocrine

Interventions

Test group: 2 small eggs/day + energy-restricted diet (~500 Kcal/day following British Heart Foundation [BHF] guidelines). Control group: energy-restricted diet alone. 12 week intervention.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy adult male and females aged 18-55 years 2. Body Mass Index (BMI) that classifies them as being overweight >25, <40

Exclusion criteria

Exclusion criteria: 1. BMI >40 (morbid obesity) 2. Total plasma cholesterol >6.5 mM 3. No prescribed medication 4. No dietary supplements including 'cholesterol-lowering' foods (e.g. benecol or flora proactive) or existing diets or having lost >3 kg in preceding 2 months

Design outcomes

Primary

Measure	Time frame
1. Total plasma cholesterol 2. Low-density lipoprotein (LDL) cholesterol 3. Body weight	—

Secondary

Measure	Time frame
Plasma cholesterol precursors (mevalonate and lathosterol) and plant sterols (beta-sitosterol and campesterol) as markers of cholesterol synthesis and absorption respectively	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026