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Quality of life after open fracture of the leg bones

Quality of life after open extremity trauma (QUINTET): a prospective, multi-centre, international study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN31179727
Enrollment
200
Registered
2022-07-06
Start date
2022-06-01
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open lower extremity fractures Injury, Occupational Diseases, Poisoning Fracture of lower limb, level unspecified

Interventions

Recruited patients complete questionnaires that measure their quality of life while in the hospital to understand their quality of life before and shortly after an open fracture. This is repeated at 3

Sponsors

University of Oxford
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients admitted with an open lower limb fracture

Exclusion criteria

Exclusion criteria: Patients unable to consent

Design outcomes

Primary

MeasureTime frame
Quality of life measured with the 5-Dimension EuroQol (EQ-5D-3L) and Short Form 12 (SF-12) instruments twice during the acute admission. For the first assessment patients will be asked to appraise their quality of life before their injury and for the second assessment their quality of life at present while an inpatient. This assessment will be repeated at 3 months and 12 months post-injury.

Secondary

MeasureTime frame
Clinical outcomes (wound infection, deep infection, non-union, amputation) collected from clinical notes during the period of time that the patient is enrolled in the study (12 months)

Countries

Austria, Chile, England, Netherlands, Spain, Sudan, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026