Assessment of intraoperative microaspiration

Comparative study between a cylindrical cuffed endotracheal tube, a polyurethane tapered shaped cuffed and a PVC tapered shaped cuffed endotracheal tube with respect to intraoperative microaspiration

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN30971515

Enrollment

Registered

2011-08-11

Start date

2008-10-15

Completion date

Unknown

Last updated

2017-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar surgery Surgery Lumbar surgery

Interventions

We aim for 22-24 patients/group, the groups differ from each other by the cuff used: group 1 traditional cylindrical PVC cuff, group 2 tapered shape polyurethane (PU) cuff and group 3 tapered shape P

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients sheduled for lumbar surgery 2. Age >17 years and < 75 years

Exclusion criteria

Exclusion criteria: Comprised narrowed laryngeal or tracheal lumen with the inability of intubation

Design outcomes

Primary

Measure	Time frame
Microaspiration as assessed with methylthioninium chloride. We introduced Methylthioninium chloride as dye solution to demonstrate potential aspiration of oropharyngeal secretions along the endotracheal cuff. By means of bronchoscopy we checked the descent of the dye solution.	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

Belgium

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026